منابع مشابه
Robustness, evolvability, and neutrality.
Biological systems, from macromolecules to whole organisms, are robust if they continue to function, survive, or reproduce when faced with mutations, environmental change, and internal noise. I focus here on biological systems that are robust to mutations and ask whether such systems are more or less evolvable, in the sense that they can acquire novel properties. The more robust a system is, th...
متن کاملBalancing Robustness and Evolvability
2190 O ne of the most important features of biology is the ability of organisms to persist in the face of changing conditions. Consider the remarkable fact that every organism alive today is the product of billions of generations in which its progenitors, without fail, managed to produce progeny that survived to reproduce. To achieve this consistency, organisms must have a balance between robus...
متن کاملRobustness of Evolvability
A framework for analyzing the computational capabilities and the limitations of the evolutionary process of random change guided by selection was recently introduced by Valiant [Val06]. In his framework the process of acquiring a complex functionality is viewed as a constrained form of PAC learning. In addition to the basic definition, a number of natural variants of the evolvability model were...
متن کاملRobustness and evolvability in genetic regulatory networks.
Living organisms are robust to a great variety of genetic changes. Gene regulation networks and metabolic pathways self-organize and reaccommodate to make the organism perform with stability and reliability under many point mutations, gene duplications and gene deletions. At the same time, living organisms are evolvable, which means that these kind of genetic perturbations can eventually make t...
متن کاملRobustness and evolvability: a paradox resolved.
Understanding the relationship between robustness and evolvability is key to understand how living things can withstand mutations, while producing ample variation that leads to evolutionary innovations. Mutational robustness and evolvability, a system's ability to produce heritable variation, harbour a paradoxical tension. On one hand, high robustness implies low production of heritable phenoty...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Trends in Genetics
سال: 2010
ISSN: 0168-9525
DOI: 10.1016/j.tig.2010.06.002